Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | CDC14B | O60729 | 1/20 | 0.37 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379709 | 0.87 | MAOA (0.53) | MAPTMAOAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8115088 | 0.86 | CRHR1 (0.43) | MAPTTSHRNPSR1MAOAKDM4E | |
| SCHEMBL27836600 | 0.83 | ELANE (0.43) | SMN1; SMN2CYP3A4XDHELANE | |
| SCHEMBL27854632 | 0.81 | FAAH (0.40) | MAOAALDH1A1XDHELANE | |
| SCHEMBL27854700 | 0.81 | FAAH (0.40) | MAOAALDH1A1XDHELANE | |
| SCHEMBL27836590 | 0.81 | FAAH (0.40) | MAOAALDH1A1XDHELANE | |
| SCHEMBL6962162 | 0.81 | MAPT (0.50) | MAPTTSHRKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL16559095 | 0.81 | MAPT (0.47) | MAPTTSHRNPSR1MAOAKDM4E | |
| SCHEMBL16559118 | 0.80 | MAPT (0.38) | MAPTTSHRNPSR1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6954185 | 0.80 | MAPT (0.49) | MAPTTSHRNPSR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066000-A1 | Metal Complexes and Electroluminescent Devices Comprising These Metal Complexes | MERCK PATENT GMBH (DE) | 2018-03-08 | — | — | US | disclosed |
| US-20170365786-A1 | COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE METAL COMPLEX AND TO ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-20170365785-A1 | COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE SALT, AND ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-9815940-B2 | Polymers containing substituted triarylamine units and electroluminescent devices containing said polymers | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20150069303-A1 | POLYMERS CONTAINING SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS | MERCK PATENT GMBH (DE) | 2015-03-12 | — | — | US | disclosed |
| EP-0929299-A4 | SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA(b)BENZOFURANS | LILLY CO ELI (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-0929299-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA(b)BENZOFURANS | ELI LILLY AND COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998008502-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA[b]BENZOFURANS | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066000-A1 | Metal Complexes and Electroluminescent Devices Comprising These Metal Complexes | OCIAD2, OCIAD1, ICOSLG | MAPT 1029/4885TSHR 1825/4885NPSR1 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.