Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 17/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117173 | 0.79 | CTSK (0.50) | CTSKCTSBCTSS | |
| SCHEMBL8105816 | 0.76 | CTSK (0.62) | CTSKCTSBCTSS | |
| SCHEMBL27914166 | 0.76 | RBP4 (0.70) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL27896680 | 0.76 | RBP4 (0.70) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL8096763 | 0.74 | CTSK (0.62) | CTSKCTSBCTSS | |
| SCHEMBL8111806 | 0.71 | CTSK (0.57) | CTSKCTSBCTSS | |
| SCHEMBL22394182 | 0.71 | RBP4 (0.74) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL8109815 | 0.71 | CTSK (0.69) | CTSKCTSBCTSS | |
| SCHEMBL8105988 | 0.71 | CTSK (0.69) | CTSKCTSBCTSS | |
| SCHEMBL8100339 | 0.71 | CTSK (0.57) | CTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |