Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127365 | 0.95 | LMNA (0.41) | CTSDALDH1A1LMNARAB9ATRPM8 | |
| SCHEMBL8121415 | 0.94 | CTSD (0.36) | CTSDALDH1A1LMNAGAATSHR | |
| SCHEMBL8127523 | 0.88 | NPY1R (0.33) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL8114831 | 0.88 | EPOR (0.39) | CTSDALDH1A1NR1H3KMT2A | |
| SCHEMBL8120799 | 0.88 | EPOR (0.42) | CTSDALDH1A1LMNAKDM4ENR1H3 | |
| SCHEMBL8125877 | 0.87 | MEN1 (0.46) | CTSDALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL8119581 | 0.86 | NPY1R (0.40) | — | |
| SCHEMBL8526325 | 0.86 | MAPT (0.35) | CTSDALDH1A1MAPTHTTMEN1 | |
| SCHEMBL8120144 | 0.86 | EPOR (0.35) | MEN1KMT2A | |
| SCHEMBL8111322 | 0.85 | NPY1R (0.32) | ALDH1A1LMNAMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |