SCHEMBL811385

SCHEMBL811385

CC(C)(c1ccccc1)c1ccc(N(c2ccccc2)C(C)(C)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NR3C2 P08235 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
AR P10275 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
HTR6 P50406 1/20 0.37
ESRRG P62508 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HSD17B10 Q99714 1/20 0.37
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19440984 0.92 ALDH1A1 (0.42) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL2038162 0.89 KCNN4 (0.42) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL8061599 0.87 KCNN4 (0.41) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL24206107 0.86 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL23331672 0.83 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL20629502 0.83 RAB9A (0.45) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL1591676 0.81 ALDH1A1 (0.56) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL19774510 0.81 L3MBTL1 (0.41) CYP3A4ALDH1A1SMN1; SMN2TSHRESRRG
SCHEMBL9066832 0.80 MAPT (0.48) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL28364629 0.80 MAPT (0.48) CYP3A4ALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279852-B Rubber composition for flexible couplings 现代自动车株式会社 2020-07-14 CN claimed
EP-3956395-A1 THERMOPLASTIC ELASTOMER COMPOSITION AS ADHESIVE SYSTEM FOR VULCANIZED RUBBER BASED ON CROSS-LINKED RUBBER Kraiburg TPE GmbH & Co. KG (DE) 2022-02-23 EP disclosed
EP-3956398-A1 USE OF A THERMOPLASTIC ELASTOMER COMPOSITION TO PRODUCE A FLOORING SURFACE, AND FLOORING SURFACE Gezolan AG (CH) 2022-02-23 EP disclosed
US-20210347969-A1 THERMOPLASTIC ELASTOMER COMPOSITION OF AN ELASTOMER AND A NON-ELASTOMERIC POLYOLEFIN WHICH IS FUNCTIONALIZED WITH AN ANHYDRIDE OF AN ORGANIC CARBOXYLIC ACID KRAIBURG TPE GMBH & CO. KG (DE) 2021-11-11 US disclosed
EP-3284785-B1 THERMOPLASTIC ELASTOMER COMPOSITION FOR ADHESION ON CROSSLINKED DIENE RUBBERS KRAIBURG TPE GMBH & CO KG (DE) 2021-11-03 EP disclosed
WO-2020212138-A1 USE OF A THERMOPLASTIC ELASTOMER COMPOSITION TO PRODUCE A FLOORING SURFACE, AND FLOORING SURFACE GEZOLAN AG (CH) 2020-10-22 WO disclosed
WO-2020211900-A1 THERMOPLASTIC ELASTOMER COMPOSITION AS ADHESIVE SYSTEM FOR VULCANIZED RUBBER BASED ON CROSS-LINKED RUBBER KRAIBURG TPE GMBH & CO. KG (DE) 2020-10-22 WO disclosed
CN-106279852-B Rubber composition for flexible couplings 现代自动车株式会社 2020-07-14 CN disclosed
US-10703898-B2 Thermoplastic elastomer composition for adhesion to crosslinked diene rubbers KRAIBURG TPE GMBH & CO. KG (DE) 2020-07-07 US disclosed
US-10647836-B2 Thermoplastic elastomer composition of an elastomer, a non-elastomeric polyolefin, and a thermoplastic elastomer based on polyolefin block copolymers KRAIBURG TPE GMBH & CO. KG (DE) 2020-05-12 US disclosed
EP-1770119-B1 Crosslinkabe elastomer compositions, process for preparation, and use thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-11-25 EP disclosed
US-20090247690-A1 CROSSLINKABLE COMPOSITIONS, THERMOPLASTIC ELASTOMERS OBTAINABLE THEREFROM AND THEIR USE LANXESS DEUTSCHLAND GMBH (DE) 2009-10-01 US disclosed
US-20090227725-A1 CROSSLINKABLE COMPOSITIONS, THERMOPLASTIC ELASTOMERS OBTAINABLE THEREFROM AND THEIR USE LANXESS DEUTSCHLAND GMBH (DE) 2009-09-10 US disclosed
EP-2098570-A1 Crosslinkable compositions, thermoplastic elastomers derived from same and use thereof Lanxess Deutschland GmbH (DE) 2009-09-09 EP disclosed
EP-2098566-A1 Networkable compounds, thermoplastic elastomers derived from same and use thereof Lanxess Deutschland GmbH (DE) 2009-09-09 EP disclosed
EP-1760112-B1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORP (JP) 2009-09-02 EP disclosed
EP-1762593-B1 Crosslinkable Compositions, thermoplastic elastomers obtained therefrom and their use LANXESS DEUTSCHLAND GMBH (DE) 2009-04-29 EP disclosed
EP-1770119-A1 Crosslinkabe elastomer compositions, process for preparation, and use thereof Lanxess Deutschland GmbH (DE) 2007-04-04 EP disclosed
EP-1762593-A1 Crosslinkable Compositions, thermoplastic elastomers obtained therefrom and their use Lanxess Deutschland GmbH (DE) 2007-03-14 EP disclosed
US-20070055018-A1 Crosslinkable compositions, thermoplastic elastomers obtainable therefrom and their use ARLANXEO DEUTSCHLAND GMBH (DE) 2007-03-08 US disclosed