Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364629 | 0.96 | MAPT (0.48) | MAPTALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2038162 | 0.85 | KCNN4 (0.42) | MAPTALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20629502 | 0.83 | RAB9A (0.45) | MAPTALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL8061599 | 0.83 | KCNN4 (0.41) | MAPTALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL811385 | 0.80 | ESR1 (0.50) | ALDH1A1CYP3A4KDM4ETSHRMAPK1 | |
| SCHEMBL8745890 | 0.79 | CYP3A4 (0.58) | MAPTALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL16863748 | 0.78 | MAPT (0.42) | MAPTALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL19774510 | 0.77 | L3MBTL1 (0.41) | MAPTALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL21208371 | 0.77 | CYP2D6 (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL19440984 | 0.77 | ALDH1A1 (0.42) | MAPTALDH1A1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326223-B1 | Copolymer composition | SHELL INT RESEARCH (NL) | 1996-05-08 | — | — | EP | disclosed |
| EP-0326223-A2 | Copolymer composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-08-02 | — | — | EP | disclosed |