SCHEMBL811396

SCHEMBL811396

CCN(CC)S(=O)(=O)c1cccc(Cl)c1

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
SMN1; SMN2 Q16637 6/20 0.69
TSHR P16473 4/20 0.69
LMNA P02545 5/20 0.58
MAPT P10636 4/20 0.55
VCAM1 P19320 1/20 0.53
HTT P42858 1/20 0.52
HCRTR2 O43614 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GAA P10253 1/20 0.49
GFER P55789 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197477 0.81 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL9860335 0.80 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL811119 0.79 HTR2A (0.55) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL29405930 0.79 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL2480051 0.79 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL14376200 0.79 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL9321475 0.79 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL264279 0.79 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL11183208 0.78 PGR (0.54) ALDH1A1LMNAMAPTHTTHCRTR2
SCHEMBL30487713 0.77 PSIP1 (0.56) ALDH1A1LMNAMAPTHCRTR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
EP-2390241-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 US disclosed
US-20110256790-A1 THERMAL INSULATION CONTAINING SUPPLEMENTAL INFRARED RADIATION ABSORBING MATERIAL SAINT-GOBAIN ISOVER (FR) 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 ALDH1A1 46/4885SMN1; SMN2 2997/4885TSHR 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.