Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120241 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8114296 | 0.84 | CHRNB2 (0.56) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8121446 | 0.84 | CHRNB2 (0.56) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL9264718 | 0.83 | SCD5 (0.49) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL9264284 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8139425 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8121245 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL9254476 | 0.81 | CHRNB2 (0.51) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8104991 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL21163196 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588917-B1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LAB (US) | 2000-11-08 | — | — | EP | disclosed |
| US-5409946-A | Antiepileptic agent | ABBOTT LABORATORIES (US) | 1995-04-25 | — | — | US | disclosed |