SCHEMBL8115608

SCHEMBL8115608

COc1ccc(C2(c3ccc(OC)cc3)OC(=O)CC(=O)O2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
RAB9A P51151 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HTT P42858 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRL1 P41146 1/20 0.39
HPGD P15428 2/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8107180 0.80 HCAR2 (0.47) MEN1MAPTKMT2AALDH1A1SLC6A3
SCHEMBL8114661 0.75 HSD11B1 (0.36) MAOBMAOAMEN1KMT2AALDH1A1
SCHEMBL8115288 0.75 KMT2A (0.40) MAOBMAOAMEN1KMT2AALDH1A1
SCHEMBL8115606 0.74 GLA (0.49) GLANPSR1MEN1MAPTKMT2A
SCHEMBL17024451 0.72 CA1 (0.48) NPSR1CA12CA1CA2CA7
SCHEMBL17064151 0.71 ALDH1A1 (0.54) GLANPSR1ALDH1A1HTTHPGD
SCHEMBL18287951 0.69 CA1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL16543025 0.69 CA1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL6400054 0.68 CHRNA1 (0.40) GLANPSR1CA1CA2CA7
SCHEMBL8115480 0.68 CA12 (0.42) NPSR1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed