Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8854854 | 1.00 | — | — | |
| Water SCHEMBL8502325 | 0.92 | CA4 (0.43) | CA4FAHD1MEN1LDHABLM | |
| SCHEMBL11342601 | 0.92 | CA1 (0.33) | CA4FAHD1CA1CA2 | |
| SCHEMBL1537707 | 0.92 | CA4 (0.43) | CA4FAHD1MEN1LDHABLM | |
| SCHEMBL2349640 | 0.92 | CA1 (0.33) | CA4FAHD1CA1CA2 | |
| Zinc Ion SCHEMBL3269961 | 0.92 | CA1 (0.33) | CA4FAHD1CA1CA2 | |
| SCHEMBL545006 | 0.92 | — | — | |
| SCHEMBL2349639 | 0.92 | CA1 (0.33) | CA4FAHD1CA1CA2 | |
| SCHEMBL4542250 | 0.92 | CA1 (0.33) | CA4FAHD1CA1CA2 | |
| SCHEMBL566224 | 0.92 | CA1 (0.33) | CA4FAHD1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585038-B1 | Alkali containing silica solution | CROSFIELD JOSEPH & SONS (GB) | 2000-07-26 | — | — | EP | disclosed |