Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473722 | 0.82 | CLCN2 (0.41) | FOLH1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL5597933 | 0.81 | ALDH1A1 (0.36) | CYP1A1CYP1A2CYP1B1FOLH1ALDH1A1 | |
| SCHEMBL9579734 | 0.81 | FOLH1 (0.35) | CYP1A1CYP1A2CYP1B1FOLH1ALDH1A1 | |
| SCHEMBL11388477 | 0.81 | ALDH1A1 (0.44) | FOLH1ALDH1A1KMT2AALOX15MAPT | |
| SCHEMBL8517295 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AALOX15MAPT | |
| SCHEMBL3135339 | 0.77 | FOLH1 (0.41) | CYP1A2FOLH1PTPN1ALDH1A1LMNA | |
| SCHEMBL2222912 | 0.75 | CES2 (0.41) | FOLH1PTPN1ALDH1A1LMNAKMT2A | |
| SCHEMBL30565103 | 0.75 | FOLH1 (0.59) | FOLH1ALDH1A1ALOX15MAPTHPGD | |
| SCHEMBL445508 | 0.75 | FOLH1 (0.59) | FOLH1ALDH1A1ALOX15MAPTHPGD | |
| SCHEMBL8069191 | 0.74 | KDM4E (0.48) | PTPN1ALDH1A1ALOX15MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693061-B1 | FUNGICIDAL OXAZOLYL AND OXADIAZOLYL DERIVATIVES | ZENECA LTD (GB) | 2000-11-22 | — | — | EP | disclosed |
| EP-0693061-A1 | FUNGICIDAL OXAZOLYL AND OXADIAZOLYL DERIVATIVES | ZENECA LIMITED (GB) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022844-A1 | FUNGICIDAL OXAZOLYL AND OXADIAZOLYL DERIVATIVES | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |