SCHEMBL445508

SCHEMBL445508

O=C(O)c1ccccc1CBr

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.59
ALDH1A1 P00352 5/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.53
HMGB1 P09429 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HPGD P15428 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TP53 P04637 1/20 0.47
HTT P42858 1/20 0.47
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30565103 1.00 FOLH1 (0.59) FOLH1ALDH1A1ALOX15TSHRHMGB1
Hydrochloric Acid SCHEMBL3312470 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRHMGB1
Thiophene SCHEMBL5483607 0.89 FOLH1 (0.49) FOLH1ALDH1A1ALOX15TSHRHMGB1
SCHEMBL3135339 0.84 FOLH1 (0.41) FOLH1ALDH1A1ALOX15TSHRSMN1; SMN2
SCHEMBL8329762 0.84 FOLH1 (0.54) FOLH1ALDH1A1ALOX15TSHRHMGB1
SCHEMBL7677994 0.83 POLB (0.43) FOLH1ALDH1A1ALOX15TSHRHMGB1
SCHEMBL3306402 0.83 FOLH1 (0.66) FOLH1ALDH1A1ALOX15TSHRHMGB1
SCHEMBL4448226 0.83 ALDH1A1 (0.46) FOLH1ALDH1A1ALOX15TSHRHMGB1
SCHEMBL2222912 0.82 CES2 (0.41) FOLH1ALDH1A1ALOX15TSHRHPGD
SCHEMBL70392 0.81 FOLH1 (0.76) FOLH1ALDH1A1ALOX15TSHRHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 994 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176789-A Novel amidino-containing iNOS inhibitor with neuroprotection function, and preparation method and application thereof 中国药科大学 2024-12-24 CN claimed
CN-118899115-A Copper-clad aluminum power cable 天通线缆有限公司 2024-11-05 CN claimed
CN-117567417-B Preparation and application of benzamide compounds 山东绿霸化工股份有限公司 2024-09-20 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117567417-A Preparation and application of benzamide compounds 山东绿霸化工股份有限公司 2024-02-20 CN claimed
CN-117482117-A ATP-responsive manganese-based bacterial composite material and preparation method and application thereof 浙江大学 2024-02-02 CN claimed
CN-117430497-A Method for synthesizing (o, m, p) bromomethylbenzoic acid or phenylacetic acid 山东碳氢生物化工有限公司 2024-01-23 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-114621194-B 4-methylene-N-hydroxybenzoamide compound and application thereof 沈阳药科大学 2023-08-29 CN claimed
CN-115466555-B Preparation method of antibacterial surface functional film layer of neodymium-iron-boron magnet 浙江中杭新材料科技有限公司 2023-06-30 CN claimed
US-20060264664-A1 Esterification of an exchange solvent enriched composition EASTMAN CHEMICAL COMPANY 2006-11-23 US claimed
US-20060264657-A1 Process to enrich a carboxylic acid composition ALPEK POLYESTER, S.A. DE C.V. (MX) 2006-11-23 US claimed
US-20060264662-A1 Esterification of an enriched composition EASTMAN CHEMICAL COMPANY 2006-11-23 US claimed
US-20060264659-A1 Process to produce an enriched composition through the use of a catalyst removal zone and an enrichment zone ALPEK POLYESTER, S.A. DE C.V. (MX) 2006-11-23 US claimed
US-20060264658-A1 Process to produce an enriched composition ALPEK POLYESTER, S.A. DE C.V. (MX) 2006-11-23 US claimed
WO-2006125116-A2 ESTERIFICATION OF AN ENRICHED COMPOSITION EASTMAN CHEMICAL COMPANY (US) 2006-11-23 WO claimed
WO-2006125199-A2 A PROCESS TO PRODUCE A POST CATALYST REMOVAL COMPOSITION EASTMAN CHEMICAL COMPANY (US) 2006-11-23 WO claimed
EP-0884096-B1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use KOCH MEMBRANE SYSTEMS INC (US) 2005-09-14 EP claimed
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US claimed
EP-0884096-A1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use Crosswinds, Inc. (US) 1998-12-16 EP claimed