Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280625 | 0.90 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3093625 | 0.87 | AKR1C3 (0.55) | ALDH1A1TSHRMAPTGAAPTPN1 | |
| SCHEMBL30565103 | 0.84 | FOLH1 (0.59) | FOLH1ALDH1A1TSHRMAPTALOX15 | |
| SCHEMBL2222912 | 0.84 | CES2 (0.41) | FOLH1ALDH1A1TSHRALOX15GAA | |
| SCHEMBL445508 | 0.84 | FOLH1 (0.59) | FOLH1ALDH1A1TSHRMAPTALOX15 | |
| SCHEMBL4440969 | 0.84 | CES2 (0.39) | ALDH1A1TSHRMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL4445169 | 0.84 | CES2 (0.39) | ALDH1A1TSHRMAPTGAASMN1; SMN2 | |
| SCHEMBL4441884 | 0.84 | RECQL (0.49) | ALDH1A1MAPTALOX15TP53SMN1; SMN2 | |
| SCHEMBL4438718 | 0.84 | RECQL (0.45) | ALDH1A1TSHRMAPTALOX15TP53 | |
| SCHEMBL5502483 | 0.82 | GSTA1 (0.50) | ALDH1A1MAPTALOX15LMNAGSTA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701345-B2 | Car activator agents for cyclophosphamide-based treatments of cancer | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-07-18 | — | — | US | disclosed |
| US-20200352915-A1 | CAR ACTIVATOR AGENTS FOR CYCLOPHOSPHAMIDE-BASED TREATMENTS OF CANCER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-12 | — | — | US | disclosed |
| WO-2018236856-A1 | CAR ACTIVATOR AGENTS FOR CYCLOPHOSPHAMIDE-BASED TREATMENTS OF CANCER | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-12-27 | — | — | WO | disclosed |
| CN-103372461-B | Chiral emulsion catalyst as well as preparation method and application thereof | DALIAN CHEMICAL PHYSICS INST | 2014-12-10 | — | — | CN | disclosed |
| CN-103372461-A | Chiral emulsion catalyst as well as preparation method and application thereof | DALIAN CHEMICAL PHYSICS INST | 2013-10-30 | — | — | CN | disclosed |
| US-7642357-B2 | Iridium complexes | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-01-05 | — | — | US | disclosed |
| EP-2061754-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2009-05-27 | — | — | EP | disclosed |
| US-20090036696-A1 | IRIDIUM COMPLEXES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| WO-2008115999-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |
| US-20080234384-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | US | disclosed |
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | disclosed |
| CN-1128755-A | Intermediate for synthesis of pesticide | RHONE POULENC AGROCHIMIE (FR) | 1996-08-14 | — | — | CN | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |
| EP-0435687-B1 | Process for isomerization of oxime ethers | SUMITOMO CHEMICAL CO (JP) | 1995-03-29 | — | — | EP | disclosed |
| EP-0485069-B1 | Process for producing optically active amines | SUMITOMO CHEMICAL CO (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5130486-A | A ketoximine ether isomerized using a Lewis acid metal halide | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0435687-A2 | Process for isomerization of oxime ethers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0005380-B1 | PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER | Dynachem Corporation (US) | 1982-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036696-A1 | IRIDIUM COMPLEXES | HAX1, MLX, H1-0 | FOLH1 4324/4885ALDH1A1 1340/4885TSHR 1743/4885 |
| US-11701345-B2 | Car activator agents for cyclophosphamide-based treatments of cancer | CYP2A6, CYP2B6, CYP4A11 | FOLH1 2570/4885ALDH1A1 989/4885TSHR 1963/4885 |
| US-20080234384-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | FECH, SLC10A1, SLC40A1 | FOLH1 463/4885ALDH1A1 844/4885TSHR 611/4885 |
| US-20200352915-A1 | CAR ACTIVATOR AGENTS FOR CYCLOPHOSPHAMIDE-BASED TREATMENTS OF CANCER | CYP2A6, CYP2B6, CYP4A11 | FOLH1 2570/4885ALDH1A1 989/4885TSHR 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.