Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 6/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120344 | 0.90 | PTPN22 (0.46) | PTPN22C1RPRSS1FBP1TRPM8 | |
| SCHEMBL8117758 | 0.89 | C1R (0.48) | PTPN22C1RPRSS1FBP1CNR1 | |
| SCHEMBL8123575 | 0.88 | FBP1 (0.43) | PTPN22C1RPRSS1FBP1KMT2A | |
| SCHEMBL8125216 | 0.85 | FBP1 (0.45) | PTPN22C1RPRSS1FBP1TRPM8 | |
| SCHEMBL8109933 | 0.83 | TRPM8 (0.42) | TRPM8CNR1CNR2NR3C1PGR | |
| SCHEMBL8109538 | 0.82 | PRSS1 (0.52) | PTPN22C1RPRSS1FBP1TRPM8 | |
| SCHEMBL8117800 | 0.82 | SMN1; SMN2 (0.52) | PTPN22C1RPRSS1FBP1PTPN1 | |
| SCHEMBL8118219 | 0.81 | PTPN22 (0.47) | PTPN22C1RPRSS1FBP1TRPM8 | |
| SCHEMBL8119027 | 0.80 | PTPN22 (0.45) | PTPN22C1RPRSS1FBP1TRPM8 | |
| SCHEMBL8124695 | 0.80 | FBP1 (0.46) | PTPN22C1RPRSS1FBP1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |