Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | C1R | P00736 | 2/20 | 0.52 |
| ▸ | FBP1 | P09467 | 5/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120344 | 0.91 | PTPN22 (0.46) | PRSS1C1RFBP1PTPN22SMN1; SMN2 | |
| SCHEMBL8117976 | 0.88 | FBP1 (0.46) | PRSS1C1RFBP1PTPN22SMN1; SMN2 | |
| SCHEMBL8117758 | 0.87 | C1R (0.48) | PRSS1C1RFBP1PTPN22SMN1; SMN2 | |
| SCHEMBL8124340 | 0.83 | KAT8 (0.44) | PRSS1C1RSMN1; SMN2CASP3SENP7 | |
| SCHEMBL8124178 | 0.82 | PTPN22 (0.44) | PRSS1C1RFBP1PTPN22PTPN1 | |
| SCHEMBL8119484 | 0.82 | C1R (0.53) | PRSS1C1RFBP1PTPN22SMN1; SMN2 | |
| SCHEMBL8123575 | 0.79 | FBP1 (0.43) | PRSS1C1RFBP1PTPN22SMN1; SMN2 | |
| SCHEMBL8124222 | 0.78 | FBP1 (0.74) | FBP1PTPN2PTPN1PTPN5 | |
| SCHEMBL8119287 | 0.78 | C1R (0.49) | PRSS1C1RFBP1SMN1; SMN2CASP3 | |
| SCHEMBL8124527 | 0.76 | PTPRB (0.43) | PTPN22MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |