Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123468 | 0.85 | HPGD (0.47) | FBP1ALDH1A1KDM1APTPN2PTPN1 | |
| SCHEMBL8118139 | 0.82 | PTPN1 (0.66) | FBP1PTPN2PTPN1PTPN5MEN1 | |
| SCHEMBL8123406 | 0.81 | FBP1 (0.77) | FBP1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL8118852 | 0.81 | MEN1 (0.51) | FBP1ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL8119109 | 0.79 | ALOX15 (0.41) | FBP1ALDH1A1PTPN2PTPN1PTPN5 | |
| SCHEMBL8119662 | 0.78 | C1R (0.44) | FBP1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8118910 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL8119189 | 0.77 | PTPN22 (0.41) | MEN1KMT2ALMNAALOX15TSHR | |
| SCHEMBL8118002 | 0.75 | HPGD (0.48) | ALDH1A1KDM1AMEN1KMT2ALMNA | |
| SCHEMBL8118028 | 0.75 | MEN1 (0.49) | FBP1ALDH1A1KDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | claimed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |