Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118852 | 0.83 | MEN1 (0.51) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL8118139 | 0.81 | PTPN1 (0.66) | MEN1KMT2A | |
| SCHEMBL8125181 | 0.81 | FBP1 (0.72) | — | |
| SCHEMBL8118002 | 0.81 | HPGD (0.48) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL8118028 | 0.78 | MEN1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8119183 | 0.77 | FBP1 (0.49) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL617744 | 0.77 | ALDH1A1 (0.72) | ALDH1A1STAT3MEN1KMT2ALMNA | |
| SCHEMBL18851382 | 0.76 | MEN1 (0.59) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL8124637 | 0.75 | RAB9A (0.44) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL8123468 | 0.75 | HPGD (0.47) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | claimed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |