Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16313909 | 0.76 | GPR52 (0.66) | GPR52 | |
| SCHEMBL3174683 | 0.76 | GPR52 (0.66) | GPR52 | |
| SCHEMBL3174689 | 0.76 | GPR52 (0.66) | GPR52 | |
| SCHEMBL8482773 | 0.76 | GPR52 (0.61) | GPR52ALDH1A1 | |
| SCHEMBL8482775 | 0.76 | GPR52 (0.61) | GPR52ALDH1A1 | |
| SCHEMBL21676191 | 0.76 | KCNJ1 (0.39) | ENPP2 | |
| SCHEMBL2653485 | 0.75 | ALDH1A1 (0.64) | EPHX1ALDH1A1LMNAENPP2 | |
| SCHEMBL8307666 | 0.74 | ENPP2 (0.43) | ENPP2 | |
| SCHEMBL935251 | 0.73 | ALDH1A1 (0.54) | EPHX1ALDH1A1LMNAENPP2 | |
| SCHEMBL2225869 | 0.71 | MAOB (0.59) | ALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882016-B1 | ALKYLATED STYRENES AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC (CA) | 2000-05-31 | — | — | EP | claimed |