Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545475 | 0.83 | KDM4E (0.44) | NOTUMMEN1KMT2A | |
| SCHEMBL38657449 | 0.74 | RXRA (0.40) | SCN9ACYP2D6MAOAMAPK1ADRA1A | |
| SCHEMBL7373938 | 0.73 | SCN9A (0.48) | SCN9ACYP2D6MAOAMAPK1ADRA1A | |
| SCHEMBL440943 | 0.72 | TSHR (0.52) | SCN9ACYP2D6MAOAMAPK1ADRA1A | |
| SCHEMBL6480259 | 0.72 | POLB (0.47) | MEN1KMT2A | |
| SCHEMBL10481215 | 0.69 | MAPK1 (0.41) | MAOAMAPK1IDO1KMT2A | |
| SCHEMBL30444011 | 0.69 | NOTUM (0.50) | SCN9ACYP2D6MAOAMAPK1ADRA1A | |
| SCHEMBL7598605 | 0.69 | NOTUM (0.50) | SCN9ACYP2D6MAOAMAPK1ADRA1A | |
| SCHEMBL15757152 | 0.68 | SCN9A (0.54) | SCN9ACYP2D6MAOAMAPK1ADRA1A | |
| SCHEMBL24282610 | 0.68 | SCN9A (0.46) | SCN9ACYP2D6MAOAMAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707049-B1 | Process for the preparation of diaryldiketopyrrolopyrrole pigments | CIBA SC HOLDING AG (CH) | 2000-05-31 | — | — | EP | disclosed |
| EP-0707049-A1 | Process for the preparation of diaryldiketopyrrolopyrrole pigments | CIBA-GEIGY AG (CH) | 1996-04-17 | — | — | EP | disclosed |