Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804004 | 0.84 | ALDH1A1 (0.45) | EGLN1ALDH1A1TSHRTET2TGFBR1 | |
| SCHEMBL9175497 | 0.80 | GAA (0.50) | EGLN1ALDH1A1TSHRTET2HSD17B10 | |
| SCHEMBL9668021 | 0.78 | EGLN1 (0.50) | EGLN1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL322476 | 0.77 | GAA (0.52) | EGLN1ALDH1A1TSHRTET2HSD17B10 | |
| SCHEMBL7068975 | 0.77 | — | — | |
| SCHEMBL351192 | 0.77 | MGAM (0.52) | EGLN1ALDH1A1TSHRTET2TGFBR1 | |
| SCHEMBL6129631 | 0.76 | EGLN1 (0.54) | EGLN1LDHASRRALDH1A1TSHR | |
| SCHEMBL16046411 | 0.75 | TSHR (0.47) | EGLN1ALDH1A1TSHRTET2TGFBR1 | |
| SCHEMBL13478059 | 0.74 | ALDH1A1 (0.43) | EGLN1ALDH1A1TSHRTET2TGFBR1 | |
| SCHEMBL19618614 | 0.74 | ALDH1A1 (0.38) | EGLN1ALDH1A1TSHRTET2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710817-A | Small molecular weight coumarins near infrared fluorescent dye with large Stokes shift and synthesis method thereof | DALIAN CHEMICAL PHYSICS INST | 2015-06-17 | — | — | CN | claimed |
| EP-3426626-B1 | RESVERATROL GLYCOLATE AND TARTRATE DERIVATIVES AND SYNTHETIC METHODS THEREFOR | ELC MAN LLC (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3033316-B1 | COMPOUNDS AND METHODS FOR IMPROVING PLANT PERFORMANCE | TRIAD NAT SECURITY LLC (US) | 2020-08-05 | — | — | EP | disclosed |
| US-10117431-B2 | Compounds and methods for improving plant performance | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2018-11-06 | — | — | US | disclosed |
| US-20160345577-A1 | Compounds And Methods for Improving Plant Performance | TRIAD NATIONAL SECURITY, LLC | 2016-12-01 | — | — | US | disclosed |
| US-9446992-B2 | Compounds and methods for improving plant performance | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160220536-A1 | USE OF PHENYLMETHIMAZOLES, METHIMAZOLE DERIVATIVES, AND TAUTOMERIC CYCLIC THIONES FOR THE TREATMENT OF AUTOIMMUNE/INFLAMMATORY DISEASES ASSOCIATED WITH TOLL-LIKE RECEPTOR OVEREXPRESSION | UNIV OHIO (US) | 2016-08-04 | — | — | US | disclosed |
| EP-3033316-A1 | COMPOUNDS AND METHODS FOR IMPROVING PLANT PERFORMANCE | Los Alamos National Security, LLC (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9326972-B2 | Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression | OHIO UNIVERSITY (US) | 2016-05-03 | — | — | US | disclosed |
| US-20160045151-A1 | METHOD AND APPARATUS FOR NON-INVASIVE LIVER FUNCTION TESTING | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-02-18 | — | — | US | disclosed |
| WO-1999012903-A1 | BENZIMIDAZOLINONES, BENZOXAZOLINONES, BENZOPIPERAZINONES, INDANONES, AND DERIVATIVES THEREOF AS INHIBITORS OF FACTOR XA | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5597548-A | METABOLISM TO ACETYL COENZYME A; MEASURING GLUTAMATE ENRICHMENT PATTERN | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-01-28 | — | — | US | disclosed |
| US-5413917-A | Carbon-13 label, nuclear magnetic resonance | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-05-09 | — | — | US | disclosed |
| WO-1992001937-A2 | METHOD OF DETERMINING SOURCES OF ACETYL-COA UNDER NONSTEADY-STATE CONDITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-02-06 | — | — | WO | disclosed |
| CN-1039596-A | Preparation method in conjunction with the peptide of retroviral Protease | SMITHKLINE BECKMAN CORP (US) | 1990-02-14 | — | — | CN | disclosed |
| US-4204056-A | Process and intermediates for preparing fiber-reactive phthalocyanine dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-05-20 | — | — | US | disclosed |
| US-4191686-A | FROM SULFONYL HALIDE SUBSTITUTED PARENT BY AMIDATION WITH AROMATIC DIAMINE, DIAZOTIZING, COUPLING TO KETO SUCCINIC ESTER, CYCLIZING, COUPLING TO REACTIVE MOIETY | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |
| US-3946028-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3946027-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3943140-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10117431-B2 | Compounds and methods for improving plant performance | KYAT3, KMO, KHK | EGLN1 951/4885LDHA 2012/4885SRR 191/4885 |
| US-20160345577-A1 | Compounds And Methods for Improving Plant Performance | KYAT3, KMO, KHK | EGLN1 951/4885LDHA 2012/4885SRR 191/4885 |
| US-20160220536-A1 | USE OF PHENYLMETHIMAZOLES, METHIMAZOLE DERIVATIVES, AND TAUTOMERIC CYCLIC THIONES FOR THE TREATMENT OF AUTOIMMUNE/INFLAMMATORY DISEASES ASSOCIATED WITH TOLL-LIKE RECEPTOR OVEREXPRESSION | IRF3, TLR3, TLR4 | EGLN1 4621/4885LDHA 4806/4885SRR 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.