SCHEMBL8120940

SCHEMBL8120940

CNc1cccnc1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
GLO1 Q04760 2/20 0.38
ALOX5AP P20292 2/20 0.37
FEN1 P39748 2/20 0.37
MAPK10 P53779 1/20 0.37
SLC40A1 Q9NP59 2/20 0.37
HTR6 P50406 1/20 0.37
SLC22A12 Q96S37 1/20 0.36
NSD2 O96028 2/20 0.36
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
FTO Q9C0B1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9522703 0.80 SLC40A1 (0.41) MAPTSMN1; SMN2KDM4EMEN1NPC1
SCHEMBL26662620 0.79 MEN1 (0.40) MAPTSMN1; SMN2KDM4EMEN1NPC1
SCHEMBL31316415 0.79 MEN1 (0.40) MAPTSMN1; SMN2KDM4EMEN1NPC1
SCHEMBL8114615 0.79 ALDH1A1 (0.46) MAPTSMN1; SMN2KDM4EMEN1NPC1
SCHEMBL9038749 0.76 COMT (0.43) MAPTSMN1; SMN2KDM4EMEN1NPC1
SCHEMBL8120618 0.76 LMNA (0.40) KDM4EMEN1LMNAKMT2AGLO1
SCHEMBL9364168 0.76 JAK2 (0.41) SMN1; SMN2LMNASLC40A1FTOPOLB
SCHEMBL10516708 0.75 KDM4E (0.46) MAPTSMN1; SMN2KDM4ENPC1LMNA
SCHEMBL8105849 0.74 ALDH1A1 (0.36) MAPTSMN1; SMN2KDM4EMEN1NPC1
SCHEMBL9820371 0.74 ALDH1A1 (0.39) MAPTSMN1; SMN2KDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451468-B2 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA (JP) 2000-03-08 EP disclosed
US-5139565-A Herbicides which are safe for corn ISHIHARA SANGYO KAISHA LTD. (JP) 1992-08-18 US disclosed
EP-0451468-A1 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA, LTD. (JP) 1991-10-16 EP disclosed