Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516708 | 0.85 | KDM4E (0.46) | P2RX7LMNAKIF18ASMN1; SMN2GAA | |
| SCHEMBL9117916 | 0.83 | SLC40A1 (0.48) | POLBLMNAGAASLC40A1 | |
| SCHEMBL9118803 | 0.82 | KIF18A (0.38) | P2RX7POLBLMNAKIF18ASMN1; SMN2 | |
| SCHEMBL9213700 | 0.81 | P2RX7 (0.39) | P2RX7POLBLMNAKIF18ASMN1; SMN2 | |
| SCHEMBL9363595 | 0.79 | P2RX7 (0.49) | JAK2JAK1TYK2P2RX7POLB | |
| SCHEMBL8120940 | 0.76 | MAPT (0.39) | POLBLMNASMN1; SMN2SLC40A1FTO | |
| SCHEMBL9522703 | 0.75 | SLC40A1 (0.41) | LMNASMN1; SMN2SLC40A1TP53 | |
| SCHEMBL26662620 | 0.74 | MEN1 (0.40) | POLBLMNASMN1; SMN2SLC40A1 | |
| SCHEMBL31316415 | 0.74 | MEN1 (0.40) | POLBLMNASMN1; SMN2SLC40A1 | |
| SCHEMBL8114615 | 0.74 | ALDH1A1 (0.46) | LMNASMN1; SMN2SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388994-B1 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0388994-A1 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0232067-A2 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1987-08-12 | — | — | EP | disclosed |