Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812176 | 0.82 | LMNA (0.44) | ALDH1A1POLBKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL812175 | 0.82 | LMNA (0.44) | ALDH1A1POLBKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL811589 | 0.75 | LMNA (0.47) | ALDH1A1POLBKMT2ANPC1RAB9A | |
| SCHEMBL2672732 | 0.73 | MEN1 (0.46) | ALDH1A1KMT2AMEN1HTR2ANPC1 | |
| SCHEMBL3256286 | 0.73 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2AMEN1LMNA | |
| SCHEMBL5160741 | 0.72 | CYP2C19 (0.48) | ALDH1A1POLBBCL9CTNNB1CYP1A2 | |
| SCHEMBL5160750 | 0.72 | CYP2C19 (0.48) | ALDH1A1POLBBCL9CTNNB1CYP1A2 | |
| SCHEMBL3883313 | 0.72 | MEN1 (0.44) | ALDH1A1KMT2AMEN1HTR2AGAA | |
| SCHEMBL15661537 | 0.71 | HTR2A (0.45) | ALDH1A1POLBKMT2AMEN1HTR2A | |
| SCHEMBL11273163 | 0.71 | LOXL2 (0.46) | ALDH1A1KMT2AMEN1HTR2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345634-A1 | Optically active 4-amino-3-(4-chlorophenyl) butanoic acid | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110152572-A1 | OPTICALLY ACTIVE 4-AMINO-3-(4-CHLOROPHENYL)BUTANOIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-06-23 | — | — | US | disclosed |