Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812176 | 1.00 | LMNA (0.44) | LMNAKCNJ1KCNH2ALDH1A1POLB | |
| SCHEMBL811589 | 0.93 | LMNA (0.47) | LMNAKCNJ1KCNH2ALDH1A1POLB | |
| SCHEMBL9308781 | 0.84 | MMP8 (0.52) | LMNAKCNJ1KCNH2ALDH1A1POLB | |
| SCHEMBL7266498 | 0.83 | ALDH1A1 (0.46) | LMNAKCNJ1KCNH2ALDH1A1POLB | |
| SCHEMBL812134 | 0.82 | ALDH1A1 (0.40) | LMNAALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL2370645 | 0.82 | MMP8 (0.52) | LMNAKCNJ1KCNH2ALDH1A1POLB | |
| SCHEMBL812135 | 0.82 | LMNA (0.43) | LMNAKCNJ1KCNH2ALDH1A1POLB | |
| SCHEMBL7139929 | 0.81 | ALDH1A1 (0.49) | LMNAKCNJ1KCNH2ALDH1A1KMT2A | |
| SCHEMBL14861332 | 0.81 | MMP8 (0.57) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL14872349 | 0.81 | MMP8 (0.57) | LMNAALDH1A1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669395-B2 | Optically active 4-amino-3-(4-chlorophenyl)butanoic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-11 | — | — | US | disclosed |
| EP-2345634-B1 | Optically active 4-amino-3-(4-chlorophenyl) butanoic acid | SUMITOMO CHEMICAL CO (JP) | 2013-03-06 | — | — | EP | disclosed |
| EP-2345634-A1 | Optically active 4-amino-3-(4-chlorophenyl) butanoic acid | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |