Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625971 | 0.86 | HTR2C (0.36) | HTR2CHTR2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL8910440 | 0.81 | — | — | |
| SCHEMBL8868990 | 0.80 | KDM4E (0.39) | ALDH1A1TSHRKDM4EMEN1MAPT | |
| SCHEMBL14631751 | 0.79 | SLC6A2 (0.31) | HTR2CHTR2ASLC6A4 | |
| SCHEMBL8912772 | 0.79 | MAPT (0.38) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL7094838 | 0.78 | AKR1B1 (0.31) | — | |
| SCHEMBL4538261 | 0.77 | HTR2C (0.34) | HTR2CHTR2A | |
| SCHEMBL29756154 | 0.77 | HTR2C (0.34) | HTR2CHTR2A | |
| SCHEMBL8823964 | 0.76 | HTR2C (0.31) | HTR2CHTR2A | |
| SCHEMBL8681014 | 0.75 | ALDH1A1 (0.39) | HTR2CHTR2AALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951445-B2 | Photochromic optical article and method of producing the same | TOKUYAMA CORPORATION (JP) | 2011-05-31 | — | — | US | disclosed |
| US-7951445-B2 | Photochromic optical article and method of producing the same | TOKUYAMA CORPORATION (JP) | 2011-05-31 | — | — | US | disclosed |
| EP-0971914-B1 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO 1,2-b PYRANS AND HETEROCYCLIC PYRANS | VIVIMED LABS EUROP LTD (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20080226883-A1 | Photochromic Optical Article and Method of Producing the Same | TOKUYAMA CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080226883-A1 | Photochromic Optical Article and Method of Producing the Same | TOKUYAMA CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-0696582-B1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORP (JP) | 2000-03-22 | — | — | EP | disclosed |
| EP-0629626-B1 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORP (JP) | 1999-10-27 | — | — | EP | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |