Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910990 | 0.81 | — | — | |
| SCHEMBL8868990 | 0.81 | KDM4E (0.39) | MAPTKDM4EP2RX7LMNAMEN1 | |
| SCHEMBL8122010 | 0.79 | HTR2C (0.33) | MAPTKDM4ELMNAMEN1HTT | |
| SCHEMBL8911274 | 0.75 | CA12 (0.37) | HTTSMN1; SMN2 | |
| SCHEMBL8120470 | 0.75 | MAPT (0.44) | MAPTKDM4ELMNAMEN1HSP90AA1 | |
| SCHEMBL8911974 | 0.74 | ALDH1A1 (0.30) | MAPTKMT2A | |
| SCHEMBL8910440 | 0.74 | — | — | |
| SCHEMBL8910451 | 0.73 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL8912778 | 0.73 | TP53 (0.30) | — | |
| SCHEMBL2458273 | 0.69 | MAPT (0.47) | MAPTKDM4ELMNAMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608065-A | ADAMANTANEOSPIRO-HETEROAROMATIC PYRANS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-03-04 | — | — | US | claimed |