Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742149 | 0.93 | POLB (0.47) | POLBHTTNPSR1LMNAMCHR1 | |
| SCHEMBL27538508 | 0.92 | LMNA (0.54) | POLBHTTCNR1LMNACNR2 | |
| SCHEMBL8115002 | 0.91 | POLB (0.45) | POLBHTTNPSR1CNR1LMNA | |
| SCHEMBL8118713 | 0.91 | POLB (0.45) | POLBHTTNPSR1LMNAMCHR1 | |
| SCHEMBL8118092 | 0.88 | NLRP3 (0.46) | POLBHTTNPSR1CNR1LMNA | |
| SCHEMBL8113785 | 0.86 | HTT (0.47) | POLBHTTNPSR1LMNAMCHR1 | |
| SCHEMBL27513954 | 0.84 | MRGPRX4 (0.44) | POLBLMNAMCHR1ALDH1A1MAPT | |
| SCHEMBL8114620 | 0.84 | LMNA (0.48) | POLBLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8115188 | 0.84 | THRB (0.46) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8113653 | 0.83 | ALDH1A1 (0.44) | POLBHTTNPSR1LMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |