Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126778 | 0.91 | HSD11B1 (0.34) | HPGDKMT2AALDH1A1HSD11B1 | |
| SCHEMBL8114286 | 0.90 | OPRM1 (0.33) | TMEM97SIGMAR1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL1388418 | 0.85 | TMEM97 (0.36) | TMEM97SIGMAR1HPGDKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8126105 | 0.83 | TMEM97 (0.35) | TMEM97SIGMAR1HPGDKMT2AALDH1A1 | |
| SCHEMBL8112794 | 0.83 | F2 (0.33) | ALDH1A1HSD11B1 | |
| SCHEMBL8126579 | 0.82 | TACR1 (0.37) | ALDH1A1 | |
| SCHEMBL8115107 | 0.81 | F2 (0.33) | — | |
| SCHEMBL8121140 | 0.80 | F2 (0.36) | — | |
| SCHEMBL8127301 | 0.80 | MEN1 (0.33) | KMT2APYGL | |
| SCHEMBL8112073 | 0.78 | PSEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |