Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114286 | 0.91 | OPRM1 (0.33) | HSD11B1F2MEN1KMT2AALDH1A1 | |
| SCHEMBL8122655 | 0.91 | TMEM97 (0.33) | HSD11B1KMT2AALDH1A1HPGD | |
| SCHEMBL8112794 | 0.89 | F2 (0.33) | HSD11B1F2NPC1RAB9AALDH1A1 | |
| SCHEMBL8126579 | 0.87 | TACR1 (0.37) | F2NPC1RAB9AALDH1A1 | |
| SCHEMBL8121140 | 0.86 | F2 (0.36) | F2GAA | |
| Hydrochloric Acid SCHEMBL8111831 | 0.84 | TRPM8 (0.36) | HSD11B1TRPM8CTSKMEN1KMT2A | |
| SCHEMBL8115107 | 0.82 | F2 (0.33) | F2 | |
| SCHEMBL8112073 | 0.79 | PSEN1 (0.36) | — | |
| SCHEMBL9285632 | 0.79 | F2 (0.33) | F2ALDH1A1 | |
| SCHEMBL8126826 | 0.78 | CNR1 (0.37) | F2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |