Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112794 | 0.90 | F2 (0.33) | F2NPC1RAB9AALDH1A1 | |
| SCHEMBL8126778 | 0.87 | HSD11B1 (0.34) | F2NPC1RAB9AALDH1A1 | |
| SCHEMBL1388296 | 0.85 | TACR1 (0.39) | TACR1C3AR1 | |
| SCHEMBL8121140 | 0.84 | F2 (0.36) | F2 | |
| SCHEMBL8114286 | 0.82 | OPRM1 (0.33) | F2ALDH1A1 | |
| SCHEMBL8122655 | 0.82 | TMEM97 (0.33) | ALDH1A1 | |
| SCHEMBL8115107 | 0.80 | F2 (0.33) | F2 | |
| SCHEMBL9285632 | 0.80 | F2 (0.33) | F2ALDH1A1 | |
| SCHEMBL8126826 | 0.80 | CNR1 (0.37) | F2ALDH1A1 | |
| SCHEMBL8125954 | 0.80 | CNR1 (0.39) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |