Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599167 | 0.96 | MAOA (0.53) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| SCHEMBL29649256 | 0.96 | MAOA (0.53) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| Hydrochloric Acid SCHEMBL7258529 | 0.94 | MAOA (0.52) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| SCHEMBL30082317 | 0.88 | CYP11B2 (0.49) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| SCHEMBL3581879 | 0.88 | CYP11B2 (0.49) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| Hydrochloric Acid SCHEMBL23406550 | 0.86 | CYP11B2 (0.47) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| SCHEMBL11265174 | 0.84 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| SCHEMBL2877256 | 0.80 | MAOA (0.53) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| SCHEMBL31128508 | 0.80 | MAOA (0.53) | SIGMAR1MAOAMAOBCYP2A6PKN1 | |
| Hydrochloric Acid SCHEMBL2883050 | 0.78 | MAOA (0.52) | SIGMAR1MAOAMAOBCYP2A6PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089305-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2009-07-16 | — | — | WO | disclosed |
| EP-1015450-A1 | NOVEL PYRIDAZINE COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-07-05 | — | — | EP | disclosed |
| WO-1997045428-A1 | NOVEL PYRIDAZINE COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-12-04 | — | — | WO | disclosed |