Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mannitol SCHEMBL28834478 | 0.75 | PDE4A (0.44) | LMNAL3MBTL1ALDH1A1PDE4ATDP1 | |
| SCHEMBL27821024 | 0.75 | PDE4A (0.40) | LMNAL3MBTL1ALDH1A1RECQLPDE4A | |
| SCHEMBL6726577 | 0.75 | PDE4A (0.48) | LMNAL3MBTL1ALDH1A1PDE4ATDP1 | |
| SCHEMBL5315458 | 0.71 | LMNA (0.43) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| Mannitol SCHEMBL27910852 | 0.71 | KDM4E (0.44) | L3MBTL1ALDH1A1PDE4AMAPTKDM4E | |
| SCHEMBL29095957 | 0.70 | PDE4A (0.36) | LMNAL3MBTL1PDE4ATDP1MAPT | |
| SCHEMBL18346393 | 0.69 | LMNA (0.37) | LMNAL3MBTL1ALDH1A1RECQLTDP1 | |
| SCHEMBL978754 | 0.69 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1RECQLMAPT | |
| SCHEMBL4952243 | 0.69 | ALDH1A1 (0.44) | LMNAL3MBTL1ALDH1A1PDE4ATDP1 | |
| SCHEMBL7344923 | 0.68 | PRMT5 (0.46) | ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121296-A | ADMINISTERING TO TREAT PARASITIC INFECTION OR DISEASE OR TO TREAT INFECTIONS AND DISEASES CAUSED BY CERTAIN BACTERIAL AND PLANT TOXINS; COMPOUNDS SUCH AS SALT OF 2-PHENYL-3,4-DIHYDROXY-5-HYDROXYMETHYL-PYRROLIDINE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-09-19 | — | — | US | disclosed |