Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128511 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8124811 | 0.84 | ESR1 (0.40) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL8128370 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL8127869 | 0.78 | NPC1 (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2ADORA2A | |
| SCHEMBL4302593 | 0.72 | RAB9A (0.43) | SMN1; SMN2GAAMEN1KMT2AHTT | |
| SCHEMBL7500041 | 0.72 | CYP2C19 (0.69) | KDM4EALDH1A1SMN1; SMN2MAPTNCF1 | |
| SCHEMBL8123459 | 0.69 | LMNA (0.43) | ALDH1A1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL12669337 | 0.68 | CD38 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL14340740 | 0.68 | TLR8 (0.37) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL13621739 | 0.67 | MAPT (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708772-B1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING & MFG (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0708772-A1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002597-A1 | IMIDAZO[4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |