Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127891 | 0.88 | OPRM1 (0.64) | SLC6A4HTR1A | |
| SCHEMBL8120129 | 0.87 | HTR1A (0.56) | HTR1A | |
| SCHEMBL8133153 | 0.87 | BCHE (0.63) | SLC6A4HTR1A | |
| SCHEMBL8130150 | 0.86 | HTR1D (0.49) | HTR1A | |
| SCHEMBL29445154 | 0.84 | SLC6A4 (0.53) | SLC6A4HTR1AMAPK1 | |
| SCHEMBL6214011 | 0.84 | SLC6A4 (0.61) | SLC6A4HTR1A | |
| SCHEMBL8131987 | 0.84 | SIGMAR1 (0.65) | SLC6A4HTR1A | |
| SCHEMBL27118744 | 0.83 | TACR1 (0.49) | SLC6A4 | |
| SCHEMBL8129624 | 0.82 | GAA (0.55) | SLC6A4HTR1A | |
| SCHEMBL8133636 | 0.82 | SLC6A4 (0.57) | SLC6A4HTR1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610134-B1 | Indole derivatives as 5-HT1-like agonists | ADIR (FR) | 2000-04-05 | — | — | EP | disclosed |
| US-5348968-A | Migraines | ADIR ET COMPAGNIE (FR) | 1994-09-20 | — | — | US | disclosed |
| EP-0610134-A1 | Indole, indazole and benzisoxazole derivatives as 5-HT1-like agonists | ADIR ET COMPAGNIE (FR) | 1994-08-10 | — | — | EP | disclosed |