Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116625 | 0.90 | MTNR1A (0.56) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8132594 | 0.83 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL8126457 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL8126745 | 0.82 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8124550 | 0.78 | MTNR1A (0.48) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8128665 | 0.70 | MTNR1A (0.51) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8690384 | 0.69 | MTNR1A (0.64) | MTNR1AMTNR1BRAB9A | |
| SCHEMBL8124513 | 0.69 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8128016 | 0.69 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8127090 | 0.68 | ALDH1A1 (0.42) | MTNR1AMTNR1BNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |