Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132594 | 0.83 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL8127090 | 0.79 | ALDH1A1 (0.42) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8126745 | 0.74 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8116625 | 0.70 | MTNR1A (0.56) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8124372 | 0.70 | MTNR1A (0.58) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8126457 | 0.69 | MTNR1A (0.53) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL8123672 | 0.68 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8124550 | 0.68 | MTNR1A (0.48) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8124513 | 0.68 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8131063 | 0.67 | MTNR1A (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |