SCHEMBL812438

SCHEMBL812438

Cc1ccc(C)c2c1cnc1ccccc12

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.46
KDM4E B2RXH2 1/20 0.45
GPR3 P46089 1/20 0.45
TOP2A P11388 1/20 0.44
PDPK1 O15530 1/20 0.42
NPC1 O15118 1/20 0.39
TLR7 Q9NYK1 1/20 0.38
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19007826 0.78 GPR3 (0.52) CYP1A2KDM4EGPR3TOP2A
SCHEMBL23028710 0.77 KDM4E (0.57) CYP1A2KDM4EGPR3TOP2APDPK1
SCHEMBL1103243 0.76 TOP2A (0.51) CYP1A2KDM4EGPR3TOP2APDPK1
SCHEMBL16535871 0.74 GPR3 (0.52) CYP1A2KDM4EGPR3TOP2APDPK1
SCHEMBL19007829 0.73 CCR1 (0.50) KDM4EGPR3TOP2ANPC1TLR7
SCHEMBL19020845 0.73 GPR3 (0.68) KDM4EGPR3TOP2APDPK1NPC1
SCHEMBL3156746 0.72 CCR1 (0.52) CYP1A2KDM4EGPR3TOP2ATLR7
SCHEMBL22048797 0.72 GPR3 (0.50) KDM4EGPR3TOP2APDPK1NPC1
SCHEMBL29661797 0.72 CCR1 (0.52) CYP1A2KDM4EGPR3TOP2ATLR7
SCHEMBL1103265 0.72 NPC1 (0.50) KDM4EGPR3TOP2APDPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130027636-A1 CLASS OF BRIDGED BIPHENYLENE POLYMERS SUMITOMO CHEMICAL CO., LTD. (JP) 2013-01-31 US disclosed
US-20130027636-A1 CLASS OF BRIDGED BIPHENYLENE POLYMERS SUMITOMO CHEMICAL CO., LTD. (JP) 2013-01-31 US disclosed
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
US-8247800-B2 Triarylamine containing polymers and electronic devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-21 US disclosed
US-8247800-B2 Triarylamine containing polymers and electronic devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-21 US disclosed
US-20120010359-A1 SALICYLATE SUBSTITUTED CONJUGATED POLYMERS AND DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-20120010359-A1 SALICYLATE SUBSTITUTED CONJUGATED POLYMERS AND DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-8052894-B2 Salicylate substituted conjugated polymers and devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-08 US disclosed
US-8052894-B2 Salicylate substituted conjugated polymers and devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-08 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 US disclosed
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 US disclosed
US-20080011353-A1 Triarylamine Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-17 US disclosed
US-20080011353-A1 Triarylamine Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-17 US disclosed
EP-1576032-B1 TRICYCLIC ARYLAMINE MONOMER AND POLYMERS AND DEVICES THEREOF DOW GLOBAL TECHNOLOGIES INC (US) 2007-10-17 EP disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 CYP1A2 361/4885KDM4E 1909/4885GPR3 499/4885
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES NAT1, AHR, AR CYP1A2 309/4885KDM4E 1876/4885GPR3 258/4885
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon THEM6, PCNA, PARG CYP1A2 2904/4885KDM4E 4244/4885GPR3 3957/4885
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices TLR9, TLR5, TLR1 CYP1A2 950/4885KDM4E 2100/4885GPR3 3727/4885
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices PYM1, KCNMB4, BRD9 CYP1A2 516/4885KDM4E 503/4885GPR3 2245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.