Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713612 | 0.79 | HCRTR2 (0.44) | HCRTR2PARP1MAOADRD3LTB4R | |
| SCHEMBL8278342 | 0.79 | HCRTR2 (0.44) | HCRTR2PARP1MAOADRD3LTB4R | |
| SCHEMBL14395510 | 0.75 | LTB4R (0.43) | HCRTR2MAOADRD3LTB4RLTB4R2 | |
| SCHEMBL21536753 | 0.75 | LTB4R (0.43) | HCRTR2MAOADRD3LTB4RLTB4R2 | |
| SCHEMBL8278101 | 0.74 | HCRTR2 (0.44) | HCRTR2PARP1DRD3LTB4RLTB4R2 | |
| SCHEMBL13038051 | 0.73 | HCRTR2 (0.48) | HCRTR2PARP1DRD3DRD2DRD4 | |
| SCHEMBL22923302 | 0.73 | HCRTR2 (0.48) | HCRTR2PARP1DRD3DRD2DRD4 | |
| SCHEMBL9581223 | 0.73 | HCRTR2 (0.43) | HCRTR2PARP1DRD3DRD2DRD4 | |
| SCHEMBL7752945 | 0.68 | HTR1A (0.58) | HCRTR2PARP1CYP3A4TP53MEN1 | |
| SCHEMBL7518917 | 0.67 | PARP1 (0.41) | HCRTR2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306136-A1 | Substituted Ureas and Carbamates | ELAN PHARMACEUTICALS, INC. | 2008-12-11 | — | — | US | disclosed |
| US-7351738-B2 | Substituted ureas and carbamates | ELAN PHARMACEUTICALS, INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-20040209925-A1 | Substituted ureas and carbamates | ELAN PHARMACEUTICALS, INC. | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209925-A1 | Substituted ureas and carbamates | BACE1, BACE2, PSEN1 | HCRTR2 2052/4885PARP1 1904/4885MAOA 1195/4885 |
| US-20080306136-A1 | Substituted Ureas and Carbamates | BACE1, BACE2, APP | HCRTR2 1814/4885PARP1 2533/4885MAOA 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.