SCHEMBL9303564

SCHEMBL9303564

CCC(O)C(CCCC(=O)O)(C(=O)O)C(O)CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.40
FFAR4 Q5NUL3 2/20 0.39
FFAR1 O14842 2/20 0.39
GPR84 Q9NQS5 7/20 0.39
PPARG P37231 7/20 0.39
PPARD Q03181 7/20 0.39
PPARA Q07869 7/20 0.39
HDAC11 Q96DB2 5/20 0.39
TSHR P16473 5/20 0.39
PTPN1 P18031 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
SLC22A6 Q4U2R8 2/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
ESR1 P03372 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11214875 0.93 GPR84 (0.45) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL11333705 0.88 ALDH1A1 (0.44) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL4528638 0.82 AKR1B1 (0.41) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL812764 0.80 LMNA (0.40) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL11877026 0.79 ALDH1A1 (0.41) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL136592 0.78 LMNA (0.42) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL4522861 0.76 GPR84 (0.47) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL4522848 0.76 GPR84 (0.47) AKR1B1FFAR4FFAR1GPR84PPARG
SCHEMBL7646112 0.74 TSHR (0.42) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL3264787 0.74 AKR1B1 (0.47) AKR1B1FFAR4FFAR1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5277979-A Emulsion polymerization with a reactive compound having at least two active methylene function groups forming core-shell particles ROHM AND HAAS COMPANY (US) 1994-01-11 US disclosed
US-5243069-A Radiation curable, coatings, adhesives, binders ROHM AND HAAS COMPANY (US) 1993-09-07 US disclosed
US-5225278-A Crosslinking a methylene active compound to form a shell around a target core using either a water in oil or oil in water emulsion; time-release agents; drugs; agriculture; carbonless copying ROHM AND HAAS COMPANY (US) 1993-07-06 US disclosed
EP-0305212-B1 PROCESS FOR MICROENCAPSULATION, USES OF POLYMERS PREPARED BY SAID PROCESS, AND COMPOSITIONS CONTAINING POLYMERS PREPARED BY SAID PROCESS ROHM AND HAAS COMPANY (US) 1992-05-06 EP disclosed
EP-0081973-B2 POLYMER COMPRISING MERS OF ESTERS AND USE THEREOF IN COATING COMPOSITIONS, BINDERS OR ADHESIVE; ESTERS AND USE THEREOF AS MONOMERS, REACTIVE DILUENTS, MODIFIERS OR CROSSLINKERS ROHM AND HAAS COMPANY (US) 1990-09-12 EP disclosed
EP-0305212-A1 Process for microencapsulation, uses of polymers prepared by said process, and compositions containing polymers prepared by said process ROHM AND HAAS COMPANY (US) 1989-03-01 EP disclosed
EP-0081973-B1 POLYMER COMPRISING MERS OF ESTERS AND USE THEREOF IN COATING COMPOSITIONS, BINDERS OR ADHESIVE; ESTERS AND USE THEREOF AS MONOMERS, REACTIVE DILUENTS, MODIFIERS OR CROSSLINKERS ROHM AND HAAS COMPANY (US) 1986-09-10 EP disclosed
US-4588788-A CARBOXYETHYL ACRYLATE ESTERS ROHM AND HAAS COMPANY (US) 1986-05-13 US disclosed
EP-0081973-A1 Polymer comprising mers of esters and use thereof in coating compositions, binders or adhesive; esters and use thereof as monomers, reactive diluents, modifiers or crosslinkers ROHM AND HAAS COMPANY (US) 1983-06-22 EP disclosed