Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404737 | 0.80 | ALDH1A1 (0.52) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL8121494 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL6919183 | 0.77 | NPC1 (0.59) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL17666028 | 0.77 | PSMB5 (0.44) | ALDH1A1GLATSHRPSMB5SMN1; SMN2 | |
| SCHEMBL5495426 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL8121490 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL7379075 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL15492964 | 0.76 | ADRA2C (0.54) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL28630847 | 0.76 | HTT (0.46) | ALDH1A1GLATSHRPSMB5SMN1; SMN2 | |
| SCHEMBL2069363 | 0.76 | OPRM1 (0.56) | ALDH1A1GLATSHRSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519353-B1 | Indolizin derivatives, process for their preparation and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-08-16 | — | — | EP | claimed |