Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927016 | 0.82 | ALDH1A1 (0.69) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL17666028 | 0.81 | PSMB5 (0.44) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL26293242 | 0.81 | LMNA (0.52) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28926571 | 0.81 | NPC1 (0.54) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL28630847 | 0.80 | HTT (0.46) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL1921083 | 0.78 | NPC1 (0.59) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8128368 | 0.77 | ALDH1A1 (0.44) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL10921379 | 0.77 | ALDH1A1 (0.62) | NPC1ALDH1A1GLAHTTRAB9A | |
| Carbamic Acid SCHEMBL6468271 | 0.77 | NPC1 (0.62) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL5694553 | 0.77 | TSPO (0.72) | NPC1ALDH1A1GLAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149072-B1 | SULFONAMIDE HYDROXAMATES | HOFFMANN LA ROCHE (CH) | 2004-06-30 | — | — | EP | claimed |