SCHEMBL8128656

SCHEMBL8128656

Cc1c(F)c(Oc2csc(C(F)(F)F)c2)nc(Oc2csc(C(F)(F)F)c2)c1F

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.43
F2 P00734 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8111160 0.90 F10 (0.42) F10F2
SCHEMBL8120351 0.87 F10 (0.41) F10F2
SCHEMBL8125502 0.85 F10 (0.40) F10F2
SCHEMBL8111396 0.85 F10 (0.36) F10F2
SCHEMBL8119386 0.85 F10 (0.39) F10F2
SCHEMBL8126929 0.83 F2 (0.37) F10F2
SCHEMBL6182022 0.80 PRMT6 (0.37) F10F2
SCHEMBL8111772 0.76 F10 (0.49) F10F2
SCHEMBL6175671 0.76 F2 (0.32) F10F2
SCHEMBL8121568 0.75 LMNA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028959-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 2000-08-23 EP claimed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO claimed
EP-1028959-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 2000-08-23 EP disclosed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO disclosed