Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178955 | 0.84 | PRMT6 (0.34) | PRMT6IDH1IDH2 | |
| SCHEMBL8128656 | 0.80 | F10 (0.43) | F10F2 | |
| SCHEMBL6181367 | 0.79 | PRMT6 (0.38) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL6723685 | 0.77 | PRMT6 (0.37) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL6178123 | 0.77 | F10 (0.38) | F10F2 | |
| SCHEMBL8111160 | 0.74 | F10 (0.42) | F10F2 | |
| SCHEMBL8125502 | 0.73 | F10 (0.40) | F10F2MAPTPTGER1 | |
| SCHEMBL8120351 | 0.72 | F10 (0.41) | F10F2 | |
| SCHEMBL6176672 | 0.72 | L3MBTL1 (0.37) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL6176976 | 0.71 | PRMT6 (0.34) | PRMT6IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427719-B1 | 4-ALKYL-SUBSTITUTE THIENYLOXY-PYRIDINES | BASF AG (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-20040198609-A1 | 4-alkyl-substituted thienyloxy-pyridines | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198609-A1 | 4-alkyl-substituted thienyloxy-pyridines | CBR3, CBR1, HDHD5 | PRMT6 161/4885F10 4082/4885IDH1 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.