Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912560 | 0.90 | ITGA4 (0.45) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL30912519 | 0.90 | ITGA4 (0.45) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL28743946 | 0.86 | PPARG (0.44) | PPARGPPARAITGA4ITGB7NR1D1 | |
| SCHEMBL10785304 | 0.84 | MMP13 (0.43) | PPARGPPARAMEN1KMT2AALDH1A1 | |
| SCHEMBL25173080 | 0.83 | PPARG (0.40) | PPARGPPARAITGA4MMP13 | |
| SCHEMBL8766144 | 0.83 | CTSS (0.44) | MMP13OPRM1OPRD1 | |
| SCHEMBL6661008 | 0.83 | CTSS (0.44) | MMP13OPRM1OPRD1 | |
| SCHEMBL4778626 | 0.83 | CTSS (0.44) | MMP13OPRM1OPRD1 | |
| SCHEMBL1401042 | 0.83 | MMP13 (0.46) | ITGA4ITGB7ALDH1A1MAPTMMP13 | |
| SCHEMBL2476924 | 0.83 | MMP13 (0.46) | ITGA4ITGB7ALDH1A1MAPTMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |