Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721449 | 0.68 | ADORA3 (0.40) | HPGDNPSR1HTR4TDP1L3MBTL1 | |
| SCHEMBL8794695 | 0.63 | KDM4E (0.39) | MEN1HPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL24564675 | 0.62 | CYP1A2 (0.41) | MEN1HPGDKMT2ATDP1L3MBTL1 | |
| SCHEMBL8134482 | 0.62 | FUCA1 (0.36) | MEN1HPGDKMT2ANPSR1HTR4 | |
| SCHEMBL7537264 | 0.60 | ALDH1A1 (0.44) | MEN1HPGDKMT2ATDP1L3MBTL1 | |
| SCHEMBL8072013 | 0.60 | ALDH1A1 (0.37) | MEN1HPGDKMT2ANPSR1HTR4 | |
| SCHEMBL1570176 | 0.59 | KDM4E (0.37) | MEN1HPGDKMT2ATDP1KDM4E | |
| SCHEMBL22281200 | 0.59 | SMN1; SMN2 (0.38) | HPGDNPSR1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8603141 | 0.59 | CA1 (0.36) | MEN1HPGDKMT2AHTR4TDP1 | |
| SCHEMBL7377280 | 0.58 | KDM4E (0.42) | MEN1KMT2ATDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |