Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 14/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134581 | 0.87 | LNPEP (0.60) | LNPEPERAP2RAB9AALDH1A1ERAP1 | |
| SCHEMBL8135399 | 0.86 | LNPEP (0.58) | LNPEPERAP2RAB9ANPSR1ALDH1A1 | |
| SCHEMBL8138188 | 0.85 | LNPEP (0.57) | LNPEPERAP2RAB9AALDH1A1ROCK2 | |
| SCHEMBL8129497 | 0.83 | ALDH1A1 (0.53) | LNPEPRAB9APOLBNPSR1ALDH1A1 | |
| SCHEMBL28277699 | 0.82 | ALDH1A1 (0.68) | LNPEPRAB9APOLBNPSR1ALDH1A1 | |
| SCHEMBL28277702 | 0.82 | ALDH1A1 (0.68) | LNPEPRAB9APOLBNPSR1ALDH1A1 | |
| SCHEMBL16993931 | 0.80 | TSHR (0.55) | RAB9AALDH1A1ROCK2ROCK1 | |
| SCHEMBL30452554 | 0.80 | TSHR (0.55) | RAB9AALDH1A1ROCK2ROCK1 | |
| SCHEMBL8129491 | 0.80 | KMT2A (0.62) | RAB9APOLBALDH1A1HDAC1HDAC8 | |
| SCHEMBL8130237 | 0.79 | RAB9A (0.70) | LNPEPRAB9AALDH1A1HDAC8MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720601-B1 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2000-10-25 | — | — | EP | disclosed |
| US-5919829-A | Gastrin and cck receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | disclosed |
| EP-0720601-A1 | GASTRIN AND CCK RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995004720-A2 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 1995-02-16 | — | — | WO | disclosed |