Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058109 | 0.87 | KMT2A (0.55) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL9054261 | 0.84 | MAPT (0.57) | KMT2ANPC1RAB9AMEN1HDAC1 | |
| SCHEMBL14799014 | 0.80 | SMN1; SMN2 (0.53) | KMT2ANPC1RAB9AMEN1HDAC1 | |
| SCHEMBL8129495 | 0.80 | LNPEP (0.61) | POLBRAB9AHDAC1HDAC8HDAC6 | |
| SCHEMBL8130235 | 0.78 | RAB9A (0.67) | KMT2ANPC1RAB9AMEN1HDAC1 | |
| SCHEMBL8129497 | 0.78 | ALDH1A1 (0.53) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL7096104 | 0.78 | EPHX1 (0.55) | KMT2ANPC1RAB9AMEN1HDAC1 | |
| SCHEMBL17769825 | 0.77 | MAPT (0.61) | KMT2ANPC1RAB9AHDAC1HDAC8 | |
| SCHEMBL2430901 | 0.76 | CASR (0.67) | KMT2APOLBMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6813779 | 0.75 | MEN1 (0.55) | KMT2APOLBRAB9AMEN1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720601-B1 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2000-10-25 | — | — | EP | disclosed |
| US-5919829-A | Gastrin and cck receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | disclosed |