Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155559 | 0.86 | SIGMAR1 (0.38) | MEN1KMT2AL3MBTL1MAPTLMNA | |
| SCHEMBL8136241 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10510642 | 0.78 | CES2 (0.46) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10516761 | 0.76 | CA12 (0.34) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3190052 | 0.74 | CES2 (0.39) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10830983 | 0.73 | CES2 (0.47) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3615922 | 0.72 | MEN1 (0.44) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3615919 | 0.72 | MEN1 (0.44) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9046842 | 0.72 | CES2 (0.37) | MEN1KMT2AL3MBTL1MAPTLMNA | |
| SCHEMBL7004956 | 0.72 | ALDH1A1 (0.35) | MEN1KMT2AL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675880-B1 | QUINOLINE DISULFIDES AS INTERMEDIATES | ARCHIMICA SPA (IT) | 2000-01-05 | — | — | EP | claimed |
| EP-0675880-A1 | QUINILONE DISULFIDE AS INTERMEDIATES | ARCHIMICA S.P.A. (IT) | 1995-10-11 | — | — | EP | claimed |
| WO-1995011886-A1 | QUINILONE DISULFIDE AS INTERMEDIATES | ARCHIMICA S.P.A. (IT) | 1995-05-04 | — | — | WO | claimed |
| EP-0675880-B1 | QUINOLINE DISULFIDES AS INTERMEDIATES | ARCHIMICA SPA (IT) | 2000-01-05 | — | — | EP | disclosed |
| US-5731433-A | Process for the preparation of rufloxacin and salts thereof | ARCHIMICA SPA (IT) | 1998-03-24 | — | — | US | disclosed |
| US-5703233-A | Quinilone disulfide as intermediates | ARCHIMICA SPA (IT) | 1997-12-30 | — | — | US | disclosed |
| EP-0725785-B1 | PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS THEREOF | ARCHIMICA SPA (IT) | 1997-07-23 | — | — | EP | disclosed |
| EP-0725785-A1 | PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS THEREOF | ARCHIMICA SPA (IT) | 1996-08-14 | — | — | EP | disclosed |
| EP-0675880-A1 | QUINILONE DISULFIDE AS INTERMEDIATES | ARCHIMICA S.P.A. (IT) | 1995-10-11 | — | — | EP | disclosed |
| WO-1995011907-A1 | PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS THEREOF | ARCHIMICA S.P.A. (IT) | 1995-05-04 | — | — | WO | disclosed |
| WO-1995011886-A1 | QUINILONE DISULFIDE AS INTERMEDIATES | ARCHIMICA S.P.A. (IT) | 1995-05-04 | — | — | WO | disclosed |