Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134003 | 0.83 | RARG (0.38) | RARGF2ELANERARARARB | |
| SCHEMBL7959829 | 0.81 | ALDH1A1 (0.40) | RARGRARAIKBKB | |
| SCHEMBL8134797 | 0.78 | HPGD (0.36) | F2ELANE | |
| SCHEMBL8747650 | 0.78 | F2 (0.39) | RARGF2ELANERARARARB | |
| SCHEMBL8118651 | 0.78 | STING1 (0.44) | RARGF2ELANERARARARB | |
| SCHEMBL8747666 | 0.77 | RARG (0.31) | RARG | |
| SCHEMBL8119132 | 0.76 | STING1 (0.35) | RARGF2ELANERARARARB | |
| SCHEMBL8119126 | 0.76 | RARG (0.35) | RARGF2ELANERARARARB | |
| SCHEMBL7962141 | 0.76 | BLM (0.37) | RARGF2ELANERARARARB | |
| SCHEMBL7961925 | 0.75 | ALDH1A1 (0.33) | RARGF2ELANERARAIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551034-B1 | Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | disclosed |
| EP-1016646-A1 | Intermediates for the preparation of cephalosporines containing on the 7-position a substituted benzyloximino radical | HOECHST MARION ROUSSEL (FR) | 2000-07-05 | — | — | EP | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |