SCHEMBL8747666

SCHEMBL8747666

COCCOCOc1cc(CO[N])cc(F)c1OCOCCOC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747871 0.80 RARG (0.30) RARG
SCHEMBL8747650 0.79 F2 (0.39) RARG
SCHEMBL8129787 0.77 RARG (0.35) RARG
SCHEMBL8119126 0.77 RARG (0.35) RARGMAOB
SCHEMBL7959829 0.74 ALDH1A1 (0.40) RARG
SCHEMBL8118651 0.71 STING1 (0.44) RARGMAOB
SCHEMBL7962141 0.69 BLM (0.37) RARG
SCHEMBL8119132 0.69 STING1 (0.35) RARG
SCHEMBL7961925 0.69 ALDH1A1 (0.33) RARG
SCHEMBL9065415 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761672-A1 Cephalosporin containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments ROUSSEL UCLAF (FR) 1997-03-12 EP disclosed