Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16057332 | 0.75 | NAAA (0.46) | UBE2NL3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL11764689 | 0.75 | L3MBTL1 (0.60) | L3MBTL1PLK1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8135536 | 0.74 | L3MBTL1 (0.54) | UBE2NL3MBTL1PLK1MAPTSMN1; SMN2 | |
| SCHEMBL8123424 | 0.70 | CYP1A2 (0.45) | L3MBTL1PLK1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL50488 | 0.69 | GAA (0.72) | L3MBTL1PLK1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL10733626 | 0.68 | L3MBTL1 (0.64) | UBE2NL3MBTL1PLK1MAPTTSHR | |
| SCHEMBL11802840 | 0.68 | EGFR (0.54) | L3MBTL1PLK1MAPTRAB9AALDH1A1 | |
| SCHEMBL6341040 | 0.68 | L3MBTL1 (0.68) | L3MBTL1PLK1MAPTTSHRKMT2A | |
| SCHEMBL9046115 | 0.68 | PLK1 (0.63) | UBE2NL3MBTL1PLK1MAPTSMN1; SMN2 | |
| SCHEMBL28463603 | 0.67 | HTT (0.60) | UBE2NL3MBTL1PLK1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466408-B1 | N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production | ROHM & HAAS (US) | 2000-01-12 | — | — | EP | disclosed |
| US-5798311-A | INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0466408-A1 | N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production | ROHM AND HAAS COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |